Choosing a spectrometer

For 13C: use the Mercury 300 with the autosampler. If it does not provide a spectrum with adequate signal-to-noise, use the Varian 500 for up to 18 hours (Scheduling page (group is MCGILLNMR)) or the Bruker 500, if you can get enough signal in the three hours available at night per user. You can also book the Bruker 400 overnight (Scheduling page (group is MCGILLNMR)). You must tune the probe on the Varian 500 before running 13C experiments on it; see the notes at Instructions. See Dr. Stein for help if needed.

For 31P: the best choices are the two Bruker instruments. If you have a concentrated sample, you can use the Varian 400. The Varian 500 can be set up to do 31P, which is handy if you need to acquire over a period of time or at high temperature, but there must be a hardware change to the probe to accomplish that. See Dr. Stein for training for this.

For 19F: use the Varian 300 with the autosampler or either Bruker instrument. You may also use the Varian 500, but you need special training for this.

For 2D involving 1H: use the Varian 300, the Varian 500 or either Bruker. You must tune the probe before running 2D experiments on the Varian 500; ask Dr. Stein if you need training for this.

For experiments involving 19F-13C correlation or 13C{19F} experiments: ue the Varian 500; this requires training from Dr. Stein. If your sample is concentrated, you can use the Varian 300.

For VT (variable temperature) work: the Varian 500 is the first choice, although the two 400 MHz instruments can also do VT experiments. Check with Dr. Stein before changing the temperature because the different instruments have different operating temperatures and each must be operated within the appropriate range.